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is acutely symptomatic from a pelvic mass, because the patient will likely need surgical intervention regardless of the radiographic ndings. Postoperatively, CT or MRI imaging may be helpful particularly in cases of ovarian cancer where there is gross residual tumor remaining, and these studies may be used to follow the patient s progress through chemotherapy. Tumor markers can be useful in suggesting a diagnosis. In this patient s case, a germ cell tumor would be the most likely malignancy and obtaining serum markers for germ cell tumors would be most appropriate (Table 12.2). hCG is useful to exclude pregnancy but can also be elevated in dysgerminomas, embryonal carcinomas, polyembryomas, choriocarcinomas, and mixed germ cell tumors. AFP and LDH can be useful to follow endodermal sinus tumors and other GCTs, but laboratory results of AFP frequently will not be available for several days. In an acute setting, hCG may be available relatively quickly but it is not necessary to delay intervention while awaiting results of other tumor markers, as they will usually not change the initial management of the patient. CA-125 is another tumor marker frequently used to assess adnexal masses. It is elevated in over 80% of all women with epithelial ovarian cancer. However, other medical conditions may .net gs1 128 GS1 - 128 - Wikipedia
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